ジャーナルクラブ/Clinical Q&A

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ジャーナルクラブ

私たちの考えるジャーナルクラブは、参加者が海外文献を和訳して発表し合うというような、単なる“抄読会”とは一線を画します。試験デザインから結論に至るまでの過程を常に批判的な視点でとらえ、同様の、あるいはそれ以上のエビデンスを自分たちの施設で獲得するにはプロトコールのどの部分を手直しすればよいかなど、現場主義に徹した討論の場を提供するのがJSEPTICのジャーナルクラブです。参考までに最近のレビューをお示しします。この臨場感に惹かれたなら、今すぐJSEPTICの門戸を叩いてください。


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最新の投稿

更新日: 2017/02/13

急性期脳出血に対する積極的降圧療法

Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage.

Qureshi AI, Palesch YY, Barsan WG, et al. Intensive Blood-Pressure Lowering in Patients with Acute Cerebral Hemorrhage. N Engl J Med. 2016 Sep 15;375(11):1033-43. PMID: 27276234

更新日: 2017/02/13

抗血小板薬内服中の非外傷性脳出血に対する血小板輸血は有効か

Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial.

Baharoglu MI, Cordonnier C, Al-Shahi Salman R, et al. Platelet transfusion versus standard care after acute stroke due to spontaneous cerebral haemorrhage associated with antiplatelet therapy (PATCH): a randomised, open-label, phase 3 trial. Lancet. 2016 Jun 25;387(10038):2605-13. PMID: 27178479

更新日: 2016/05/02

頭部外傷と低体温療法

Hypothermia for Intracranial Hypertension after Traumatic Brain Injury.

Andrews PJ, Sinclair HL, Rodriguez A, et al. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. N Engl J Med. 2015 Dec 17;373(25):2403-12. PMID: 26444221

更新日: 2016/05/02

脳梗塞に対する血管内治療のメタ解析

Endovascular Thrombectomy for Acute Ischemic Stroke: A Meta-analysis.

Badhiwala JH, Nassiri F, Alhazzani W, et al. Endovascular Thrombectomy for Acute Ischemic Stroke: A Meta-analysis. JAMA. 2015 Nov 3;314(17):1832-43. PMID: 26529161

更新日: 2016/03/07

脳梗塞の体温管理と看護ケア

Temperature Management and Nursing Care of the Patient With Acute Ischemic Stroke.

Kurashvili P, Olson D. Temperature Management and Nursing Care of the Patient With Acute Ischemic Stroke. Stroke. 2015 Sep;46(9):e205-7. PMID: 26219652

更新日: 2016/01/05

第2回神経集中治療カンファレンス

The Second Neurocritical Care Research Conference.

Suarez JI, LeRoux PD. The Second Neurocritical Care Research Conference. Neurocrit Care. 2015 Jun;22(3):335-6. PMID: 25832351

更新日: 2015/11/30

脳卒中後超急性期のリハビリ

Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial.

AVERT Trial Collaboration group, Efficacy and safety of very early mobilisation within 24 h of stroke onset (AVERT): a randomised controlled trial. Lancet. 2015 Jul 4;386(9988):46-55. PMID: 25892679

更新日: 2015/11/30

脳出血ガイドライン2015

Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.

Hemphill JC 3rd, Greenberg SM, Anderson CS, et al. Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2015 Jul;46(7):2032-60. PMID: 26022637

更新日: 2015/06/08

脳梗塞 血管内治療

Endovascular therapy for ischemic stroke with perfusion-imaging selection.
Randomized assessment of rapid endovascular treatment of ischemic stroke.
A randomized trial of intraarterial treatment for acute ischemic stroke.

Campbell BC, Mitchell PJ, Kleinig TJ, et al. Endovascular therapy for ischemic stroke with perfusion-imaging selection. PMID: 25671797
Goyal M, Demchuk AM, Menon BK, et al. Randomized assessment of rapid endovascular treatment of ischemic stroke. N Engl J Med. 2015 Mar 12;372(11):1019-30. PMID: 25671798
Berkhemer OA, Fransen PS, Beumer D, et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015 Jan 1;372(1):11-20. PMID: 25517348

更新日: 2015/05/25

大脳半球梗塞管理ガイドライン

Evidence-Based Guidelines for the Management of Large Hemispheric Infarction: A Statement for Health Care Professionals from the Neurocritical Care Society and the German Society for Neuro-Intensive Care and Emergency Medicine.

Torbey MT, Bösel J, Rhoney DH, et al. Evidence-based guidelines for the management of large hemispheric infarction : a statement for health care professionals from the neurocritical care society and the german society for neuro-intensive care and emergency medicine.

更新日: 2015/05/11

ICU-AW診断ガイドライン

An official American Thoracic Society Clinical Practice guideline: the diagnosis of intensive care unit-acquired weakness in adults

Fan E, Cheek F, Chlan L, et al. An official American Thoracic Society Clinical Practice guideline: the diagnosis of intensive care unit-acquired weakness in adults. Am J Respir Crit Care Med. 2014 Dec 15;190(12):1437-46. PMID: 25496103

更新日: 2014/11/18

Glasgow Coma Scale

The Glasgow Coma Scale at 40 years: standing the test of time.

Teasdale G, Maas A, et al. The Glasgow Coma Scale at 40 years: standing the test of time. Lancet Neurol. 2014 Aug;13(8):844-54. PMID: 25030516

更新日: 2014/06/23

高齢者MCA梗塞の減圧開頭

Hemicraniectomy in Older Patients with Extensive Middle-Cerebral-Artery Stroke

Eric Jüttler, M.D., Ph.D., Andreas Unterberg, M.D., Ph.D., et al. Hemicraniectomy in Older Patients with Extensive Middle-Cerebral-Artery Stroke PMID: 24645942

更新日: 2014/06/11

脳梗塞急性期の血圧管理

Effects of Immediate Blood Pressure Reduction on Death and Major Disability in Patients With Acute Ischemic Stroke: The CATIS Randomized Clinical Trial

Jiang He, MD, PhD; Yonghong Zhang, MD, et al. Effects of Immediate Blood Pressure Reduction on Death and Major Disability in Patients With Acute Ischemic Stroke: The CATIS Randomized Clinical Trial. JAMA. 2014;311(5):479-489. PMID: 24240777

更新日: 2014/03/17

重症疾患後の認知機能

Long-term cognitive impairment after critical illness.

Pandharipande PP1, Girard TD, et al. Long-term cognitive impairment after critical illness.N Engl J Med. 2013 Oct 3;369(14):1306-16.

更新日: 2013/12/16

脳卒中患者におけるVTE予防戦略

Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial.

CLOTS (Clots in Legs Or sTockings after Stroke) Trials Collaboration, Dennis M, Sandercock P, et al. Effectiveness of intermittent pneumatic compression in reduction of risk of deep vein thrombosis in patients who have had a stroke (CLOTS 3): a multicentre randomised controlled trial.Lancet. 2013 Aug 10;382(9891):516-24.

更新日: 2013/10/21

脳出血に対する積極的な降圧

Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage

Craig S. Anderson, M.D., Ph.D., Emma Heeley, Ph.D., et al. Rapid Blood-Pressure Lowering in Patients with Acute Intracerebral Hemorrhage.N Engl J Med. 2013 Jun 20; 368 (25): 2355-65. PMID: 23713578

更新日: 2013/05/13

頭部外傷とICP

A trial of intracranial-pressure monitoring in traumatic brain injury.

Chesnut RM, Temkin N, Carney N, et al. A trial of intracranial-pressure monitoring in traumatic brain injury. N Engl J Med. 2012 ; 367: 2471-81. PMID: 23234472

更新日: 2013/03/18

重症頭部外傷の急性期管理

Early management of severe traumatic brain injury.

Rosenfeld JV, Maas AI, Bragge P, et al. Early management of severe traumatic brain injury. Lancet. 2012;380:1088-98. PMID: 22998718

更新日: 2012/11/05

頭蓋内圧亢進と高浸透圧療法

Hyperosmolar therapy for raised intracranial pressure.

Ropper AH. Hyperosmolar therapy for raised intracranial pressure. N Engl J Med. 2012 ;367 :746-52. PMID: 22913684

更新日: 2012/10/15

痙攣重積ガイドライン

Guidelines for the evaluation and management of status epilepticus.

Brophy GM, Bell R, Claassen J, et al. Guidelines for the evaluation and management of status epilepticus. Neurocrit Care. 2012; 17: 3-23. PMID: 22528274

更新日: 2012/05/14

植物状態と脳波

Bedside detection of awareness in the vegetative state.

Sarà M, Pistoia F. et al. Bedside detection of awareness in the vegetative state. Lancet. 2012; 379: 1702-3. PMID: 22559893

更新日: 2012/05/14

頭部外傷とアマンタジン

Placebo-controlled trial of amantadine for severe traumatic brain injury.

Giacino JT, Whyte J, Bagiella E, et al. Placebo-controlled trial of amantadine for severe traumatic brain injury. N Engl J Med. 2012; 366: 819-26. PMID: 22375973

更新日: 2012/03/26

脳出血とワーファリン

Resumption of oral anticoagulation after warfarin-associated intracerebral hemorrhage: yes.

Steiner T. Resumption of oral anticoagulation after warfarin-associated intracerebral hemorrhage: yes. Stroke. 2011; 42: 3661-2. Epub 2011 Nov 3. PMID: 22052514

更新日: 2012/03/19

悪性脳梗塞

Hemicraniectomy in malignant middle cerebral artery infarction.

Staykov D, Gupta R. Hemicraniectomy in malignant middle cerebral artery infarction. Stroke. 2011; 42: 513-6. Epub 2011 Jan 6. PMID: 21212397

更新日: 2011/10/03

低体温療法

Influence of mild therapeutic hypothermia after cardiac arrest on hospital mortality

van der Wal G, Brinkman S, Bisschops LL, et al. Influence of mild therapeutic hypothermia after cardiac arrest on hospital mortality. Crit Care Med. 2011; 39: 84-8. PMID: 20959784

更新日: 2011/06/02

重症頭部外傷に対する超早期低体温療法

Very early induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial.

Clifton GL, Valadka A, Zyqun D, et al. Very early induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial. Lancet Neurol. 2011; 10: 131-9. PMID: 21169065

更新日: 2011/06/02

びまん性頭部外傷の減圧開頭

Decompressive craniectomy in diffuse traumatic brain injury.

Cooper DJ, Rosenfeld JV, Murray L, et al. DECRA Trial Investigators; Australian and New Zealand Intensive Care Society Clinical Trials Group. Decompressive craniectomy in diffuse traumatic brain injury. N Engl J Med. 2011; 364: 1493-502. PMID: 21434843

更新日: 2010/08/18

The ROSE study

The Rose (Risk Stratification of Syncope in the Emergency Department) Study

Reed MJ, Newby DE, Coull AJ, et al. The Rose (Risk Stratification of Syncope in the Emergency Department) study. J Am Coll Cardiol. 2010; 55: 713-21. PMID: 20170806

更新日: 2010/07/16

解離性くも膜下出血への硫酸マグネシウムの投与について

Prophylactic intravenous magnesium sulfate for treatment of aneurysmal subarachnoid hemorrhage: A randomized, placebo-controlled, clinical study

Westermaier T, Stetter C, Vince GH, et al. Prophylactic intravenous magnesium sulfate for treatment of aneurysmal subarachnoid hemorrhage: a randomized, placebo-controlled, clinical study. Crit Care Med. 2010; 38: 1284-90. PMID: 20228677

更新日: 2010/07/09

ECASS III

Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial

Bluhmki E, Chamorro A, Dávalos A, et al. Stroke treatment with alteplase given 3.0-4.5 h after onset of acute ischaemic stroke (ECASS III): additional outcomes and subgroup analysis of a randomised controlled trial. Lancet Neurol. 2009; 8: 1095-102. Epub 2009 Oct 21. PMID: 19850525

更新日: 2009/12/24

外傷後の痙攣の長期的なリスク

Long-term risk of epilepsy after traumatic brain injury in children and young adults: a population-based cohort study

Christensen J, Pedersen MG, Pedersen CB, et al. Long-term risk of epilepsy after traumatic brain injury in children and young adults: a population-based cohort study. Lancet. 2009; 373: 1105-10. Epub 2009 Feb 21. PMID: 19233461

更新日: 2009/12/24

重症頭部外傷治療ガイドライン

Guidelines for Management of Severe Traumatic Brain Injury 3 Edition

Brain Trauma Foundation. The American Association of Neurological Surgeons, Congress of Neurological Surgeons, AANS/CNS Joint Section on Neurotrauma and Critical Care. Guidelines for the management of severe traumatic brain injury. J Neurotrauma 2007; 24(Suppl): S1-S95. PMID: 17511534-54

更新日: 2009/11/20

neuromyopathy と corticosteroids

Intensive care unit-acquired neuromyopathy and corticosteroids in survivors of persistent ARDS

Hough CL, Steinberg KP, Taylor Thompson B, et al. Intensive care unit-acquired neuromyopathy and corticosteroids in survivors of persistent ARDS. Intensive Care Med. 2009; 35: 63-8. Epub 2008 Oct 23. PMID: 18946661

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