私たちの考えるジャーナルクラブは、参加者が海外文献を和訳して発表し合うというような、単なる“抄読会”とは一線を画します。試験デザインから結論に至るまでの過程を常に批判的な視点でとらえ、同様の、あるいはそれ以上のエビデンスを自分たちの施設で獲得するにはプロトコールのどの部分を手直しすればよいかなど、現場主義に徹した討論の場を提供するのがJSEPTICのジャーナルクラブです。参考までに最近のレビューをお示しします。この臨場感に惹かれたなら、今すぐJSEPTICの門戸を叩いてください。
更新日： 2016/05/02
頭部外傷と低体温療法
Hypothermia for Intracranial Hypertension after Traumatic Brain Injury.
Andrews PJ, Sinclair HL, Rodriguez A, et al. Hypothermia for Intracranial Hypertension after Traumatic Brain Injury. N Engl J Med. 2015 Dec 17;373(25):2403-12. PMID: 26444221
更新日： 2015/11/30
脳出血ガイドライン2015
Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association.
Hemphill JC 3rd, Greenberg SM, Anderson CS, et al. Guidelines for the Management of Spontaneous Intracerebral Hemorrhage: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association. Stroke. 2015 Jul;46(7):2032-60. PMID: 26022637
更新日： 2014/12/01
頭部外傷とEPO
Effect of erythropoietin and transfusion threshold on neurological recovery after traumatic brain injury: a randomized clinical trial.
Robertson CS, Hannay HJ, et al. Effect of erythropoietin and transfusion threshold on neurological recovery after traumatic brain injury: a randomized clinical trial. JAMA. 2014 Jul 2;312(1):36-47. PMID: 25058216
更新日： 2013/03/18
重症頭部外傷の急性期管理
Early management of severe traumatic brain injury.
Rosenfeld JV, Maas AI, Bragge P, et al. Early management of severe traumatic brain injury. Lancet. 2012;380:1088-98. PMID: 22998718
更新日： 2013/03/04
重症外傷患者の出血コントロール
Haemorrhage control in severely injured patients.
Gruen RL, Brohi K, Schreiber M, et al. Haemorrhage control in severely injured patients. Lancet. 2012;380:1099-108. PMID: 22998719
更新日： 2012/05/14
頭部外傷とアマンタジン
Placebo-controlled trial of amantadine for severe traumatic brain injury.
Giacino JT, Whyte J, Bagiella E, et al. Placebo-controlled trial of amantadine for severe traumatic brain injury. N Engl J Med. 2012; 366: 819-26. PMID: 22375973
更新日： 2012/01/09
外傷性出血へのトラネキサム酸
The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial.
CRASH-2 collaborators, Roberts I, Shakur H, Afolabi A, et al. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet. 2011; 377: 1096-101. PMID: 21439633
更新日： 2011/09/26
多発外傷とステロイド
Hydrocortisone therapy for patients with multiple trauma: the randomized controlled HYPOLYTE study.
Roquilly A, Mahe PJ, Seguin P, Hydrocortisone therapy for patients with multiple trauma: the randomized controlled HYPOLYTE study. JAMA. 2011; 305: 1201-9. PMID: 21427372
更新日： 2011/06/02
重症頭部外傷に対する超早期低体温療法
Very early induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial.
Clifton GL, Valadka A, Zyqun D, et al. Very early induction in patients with severe brain injury (the National Acute Brain Injury Study: Hypothermia II): a randomised trial. Lancet Neurol. 2011; 10: 131-9. PMID: 21169065
更新日： 2011/06/02
びまん性頭部外傷の減圧開頭
Decompressive craniectomy in diffuse traumatic brain injury.
Cooper DJ, Rosenfeld JV, Murray L, et al. DECRA Trial Investigators; Australian and New Zealand Intensive Care Society Clinical Trials Group. Decompressive craniectomy in diffuse traumatic brain injury. N Engl J Med. 2011; 364: 1493-502. PMID: 21434843
更新日： 2009/12/24
外傷後の痙攣の長期的なリスク
Long-term risk of epilepsy after traumatic brain injury in children and young adults: a population-based cohort study
Christensen J, Pedersen MG, Pedersen CB, et al. Long-term risk of epilepsy after traumatic brain injury in children and young adults: a population-based cohort study. Lancet. 2009; 373: 1105-10. Epub 2009 Feb 21. PMID: 19233461
更新日： 2009/12/24
重症頭部外傷治療ガイドライン
Guidelines for Management of Severe Traumatic Brain Injury 3 Edition
Brain Trauma Foundation. The American Association of Neurological Surgeons, Congress of Neurological Surgeons, AANS/CNS Joint Section on Neurotrauma and Critical Care. Guidelines for the management of severe traumatic brain injury. J Neurotrauma 2007; 24(Suppl): S1-S95. PMID: 17511534-54
