私たちの考えるジャーナルクラブは、参加者が海外文献を和訳して発表し合うというような、単なる“抄読会”とは一線を画します。試験デザインから結論に至るまでの過程を常に批判的な視点でとらえ、同様の、あるいはそれ以上のエビデンスを自分たちの施設で獲得するにはプロトコールのどの部分を手直しすればよいかなど、現場主義に徹した討論の場を提供するのがJSEPTICのジャーナルクラブです。参考までに最近のレビューをお示しします。この臨場感に惹かれたなら、今すぐJSEPTICの門戸を叩いてください。
更新日： 2016/06/13
重症敗血症に対する抗生剤持続投与
A Multicenter Randomized Trial of Continuous versus Intermittent β-Lactam Infusion in Severe Sepsis.
Dulhunty JM, Roberts JA, Davis JS, et al. A Multicenter Randomized Trial of Continuous versus Intermittent β-Lactam Infusion in Severe Sepsis. Am J Respir Crit Care Med. 2015 Dec 1;192(11):1298-305. PMID: 26200166
更新日： 2016/05/02
感染症に対するアセトアミノフェン
Acetaminophen for Fever in Critically Ill Patients with Suspected Infection
Young P, Saxena M, Bellomo R, et al. Acetaminophen for Fever in Critically Ill Patients with Suspected Infection. N Engl J Med. 2015 Dec 3;373(23):2215-24. PMID: 26436473
更新日： 2016/03/07
新しいCVC挿入部位と合併症
Intravascular Complications of Central Venous Catheterization by Insertion Site.
Parienti JJ, Mongardon N, Mégarbane B, et al. Intravascular Complications of Central Venous Catheterization by Insertion Site. N Engl J Med. 2015 Sep 24;373(13):1220-9. PMID: 26398070
更新日： 2016/01/05
抗菌薬を減らすストラテジー
Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric).
Bretonnière C, Leone M, Milési C, et al. Strategies to reduce curative antibiotic therapy in intensive care units (adult and paediatric). Intensive Care Med. 2015 Jul;41(7):1181-96. PMID: 26077053
更新日： 2015/10/19
敗血症の定義におけるSIRS criteria
Systemic inflammatory response syndrome criteria in defining severe sepsis.
Kaukonen KM, Bailey M, Pilcher D, et al. Systemic inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med. 2015 Apr 23;372(17):1629-38. PMID: 25776936
更新日： 2015/09/07
クロルヘキシジン清拭
Chlorhexidine bathing and health care-associated infections: a randomized clinical trial.
Noto MJ, Domenico HJ, Byrne DW, et al. Chlorhexidine bathing and health care-associated infections: a randomized clinical trial. JAMA. 2015 Jan 27;313(4):369-78. PMID: 25602496
更新日： 2014/07/28
赤血球輸血と院内感染
Health Care?Associated Infection After Red Blood Cell Transfusion A Systematic Review and Meta-analysis
Jeffrey M. Rohde, MD, Derek E. Dimcheff, MD, PhD, et al. Health Care-Associated Infection After Red Blood Cell Transfusion. A Systematic Review and Meta-analysis. JAMA. 2014;311(13):1317-1326. PMID: 24691607
更新日： 2013/11/11
PICCによる静脈血栓
Risk of venous thromboembolism associated with peripherally inserted central catheters: a systematic review and meta-analysis.
Chopra V, Anand S,. et al. Risk of venous thromboembolism associated with peripherally inserted central catheters: a systematic review and meta-analysis.Lancet. 2013 Oct 19;382(9901):1328. PMID: 23697825
更新日： 2013/01/28
末梢静脈カテーテルの交換
Routine versus clinically indicated replacement of peripheral intravenous catheters: a randomised controlled equivalence trial.
Rickard CM, Webster J, Wallis MC, et al. Routine versus clinically indicated replacement of peripheral intravenous catheters: a randomised controlled equivalence trial. Lancet. 2012;380:1066-74. PMID: 22998716
